INFLAMMATION Part 3: Leukocyte Activation – PHAGOCYTOSIS
Define Phagocytosis It is A process Which involves the recognition , engulfment and digestion of Microbes, dead cells an foreign bodies. Greek word Phagein, meaning "to devour" kytos, meaning "cell",
Read MoreINFLAMMATION Part 2: Cellular Events- Leukocyte Recruitment.
What are the cellular events in inflammation General Principles The influx of the leukocytes ( neutrophils & Monocytes) to the site of injury These leukocytes ingest and destroy the injurious
Read MoreINFLAMMATION Part 1: General Concepts, Types, Vascular Changes in Acute Inflammation
Define Inflammation Inflammation is defined as a local response of living tissue to any injurious agent. This is basically a protective response needed for survival. Historical aspects: The word
Read MoreAMYLOIDOSIS: PART 3: Morphology, Diagnosis, Special stains, clinical features & Prognosis
What are the Organs Involved in Amyloidosis? The organs involved are as under Primary Amyloidosis: Heart, GIT, Respiratory tract, peripheral nerves, skin and tongue Secondary Amyloidosis: Kidney,
Read MoreAMYLOIDOSIS: PART 2: Pathogenesis & Classification
Describe the Pathogenesis of Amyloidosis The basic mechanism in the pathogenesis of amyloidosis is abnormal folding of proteins or misfolded proteins. Under normal circumanstances, these abnormal
Read MoreAMYLOIDOSIS: Part 1: Definition, Historical aspects & Properties of Amyloid
Define Amyloidosis Is a condition associated with number of inherited and inflammatory disorders in which There is deposition of Predominantly Extracellular fibrillar proteins RESULTING IN Tissue
Read MoreWARBURG EFFECT: Hallmark of CANCER. What, Why & How?
WARBURG EFFECT: Hallmark of CANCER. What, Why & How? What is Pasteur Effect? In normal cells, in the presence of adequate oxygen, ATP is generated by oxidative phosphorylation. As the oxygen
Read MoreDNA repair Defects & Cancer
In this short tutorial, i have described how defects in DNA repair results in cancer and various DNA repair genes which are involved in the repair of damaged DNA. Question &
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